The Crystal Structure of (−)589-Dinitrobis(ethylenediamine)cobalt(III) (+)589-Bis(malonato)ethylenediaminecobaltate(III)

Aguilar 589-596.QXD

Dmm019208 577..589

Loss of mitochondrial function often leads to neurodegeneration and is thought to be one of the underlying causes of neurodegenerative diseases such as Parkinson’s disease (PD). However, the precise events linking mitochondrial dysfunction to neuronal death remain elusive. PTEN-induced putative kinase 1 (PINK1) and Parkin (Park), either of which, when mutated, are responsible for early-onset PD...

Dmd061879 578..589

A recent medicinal chemistry campaign to identify positive allosteric modulators (PAMs) of metabotropic glutamate receptor subtype 5 (mGluR5) led to the discovery of potent compounds featuring an oxazolidinone structural core flanked by biaryl acetylene and haloaryl moieties. However, biotransformation studies of some of these mGluR5 PAMs demonstrated the formation of glutathione (GSH) conjugat...

Amath 546/Econ 589 Copulas

Journal of Clinical and Experimental Neuropsychology, 16, 589-596, 1994

Memory for pairs of unfamiliar children's faces was investigated in 29 children and adolescents suffering from left (LTLE) or right (RTLE) temporal-lobe epilepsy, before and after temporal-lobe surgery. Both immediate and delayed memory were tested. Before surgery, RTLE subjects performed worse than either LTLE subjects or normal children. After surgery, RTLE subjects improved significantly. Ov...